News and Publications

BlocBuster's custom correlation coeffient is the first scientific metric in the world
to be computed at exascale speed!


BlocBuster identifies multilocus correlations involving vitamin D receptor
and skin color genes:
Latitudinal clines of the human vitamin D receptor and skin color genes
Dov Tiosano et al.
G3: Genes, Genomes, Genetics, vol. 6, pp. 1251-1266, 2016


Application of BlocBuster to HapMap data reveals yin-yang sequences:
Human gephyrin is encompassed within giant functional
noncoding yin-yang sequences
Sharlee Climer, Alan R. Templeton, and Weixiong Zhang
Nature Communications, vol. 6, no. 6534, doi:10.1038/ncomms7534, 2015


BlocBuster introduced and results for psoriasis GWAS:
Allele-specific network reveals combinatorial interaction that transcends
small effects in psoriasis GWAS
Sharlee Climer, Alan R. Templeton, and Weixiong Zhang
PLoS Computational Biology, vol. 10, no. 9, e1003766, 2014


CCC introduced and results for hypertensive heart disease GWAS:
A custom correlation coefficient (CCC) approach for fast identification of
multi-SNP association patterns in genome-wide SNPs data
Sharlee Climer, Wei Yang, Lisa de las Fuentes, Victor G. Davila-Roman, and
C. Charles Gu
Genetic Epidemiology, vol. 38, no. 7, pp. 610-621, 2014